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2nd SMR MOLECULAR GLUES MEETING
Friday 21st March 2025
GSK, Gunnels Wood Road, Stevenage SG1 2FX  

This meeting is supported by:

   
                           

PROGRAMME

08.30 - 09.25 Arrival, registration and coffee
09.25 - 09.30 Welcome and introduction
 
Session 1
09.30 - 10.10 1-1 From Ligases to Molecular Glues - Strategies to Discover Novel Molecular Glues
Markus Queisser, Director, Novel Modalities Group, GSK
10.10 - 10.50 1-2 Multimodal screening strategy for discovery of novel cereblon-directing molecular glue degraders and neosubstrates
Zoran Rankovic, Director, CPD ICR
 
10.50 - 11.10 Coffee break and exhibitors
 
Session 2
11.10 - 11.50 2-1 Cooperativity: How to Discover Molecular Glues de Novo using Biophysics
Pim de Vink, ZoBio
11.50 - 12.30 2-2 Degradation of BRD9 by a novel “targeted glue”
Marta Carrara, Amphista
 
12.30 - 13.30 Lunch break and exhibitors
 
Session 3
13.30 - 14.10 3-1 Using native mass spectrometry in the search for novel molecular glues
Aneika Leney, University of Birmingham, Group Leader
14.10 - 14.50 3-2 Sticking together: Merck Health approach to molecular glue discovery
Ingo Kober, Director Molecular Pharmacology Group, Merck
 
14.50 - 15.10 Coffee break and exhibitors
 
Session 4
15.10 - 15.50 4-1 Converging Mechanisms between a Molecular Glue Degrader and Neomorphic Cancer Mutations in an E3 ligase
Brian Liau, Group Leader, Harvard University
15.50 - 16.30 4-2 Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics
Katherine Donovan, Dana Farber
16.30 - 17.10 4-3 Exploring new opportunities in induced proximity
Ed Tate, Imperial College London
 
17.10 Closing remarks and drinks reception
   

OVERVIEW
PROGRAMME