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New Perspectives on Transporters in Drug Discovery and Development: ADME and Beyond

Thursday 23rd June 2011
 
Millennium Gloucester Hotel & Conference Centre London Kensington

Programme:
09.00 Arrival, Registration and Coffee
Session 1 : Introducing Drug Transporters.  Chair - Phil Jeffery
10.00    Paul Dobson, University of Sheffield
The central importance of transporters in drug uptake.
10.45 Joseph Polli, GlaxoSmithKline, USA
What’s all the flux about? Interpretation and application of the International Transporter Consortium whitepaper and Draft EMA Guidance.
11.30 Glynis Nicholls, AstraZeneca, UK
Human transporters and relevance of preclinical models from a regulatory perspective.
12.15 Lunch

Session 2 : Drug Transporters as Targets in Modulating Disease.  Chair - Jack Allen

13.30 Scott Allen, University of Sheffield
Mitochondrial dysfunction in Motor Neurone Disease- a potential problem?
14.15 Simone Stahl, AstraZeneca, UK
The role of hepatobiliary transporters in drug-induced liver injury.
15.00 Tea
Session 3 : Drug Transporters: Challenges for ADME.  Chair - Paul Fish
15.30

Hannah Jones, Pfizer, UK
OATP transporters in hepatic clearance, a case history.

16.15 Cynthia Bosquillon, University of Nottingham
Drug transporters in the lung.
17.00 Close
 

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